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Amyotrophic lateral sclerosis (ALS), is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) responsible for controlling voluntary muscles. The disease belongs to a group of disorders known as motor neuron diseases, which are characterized by the gradual degeneration and death of motor neurons.

  • [News Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy    

    Reseacher has announced the addition of the "Stem Cell Therapy Perspectives in Treating Motor Neuron Diseases: ALS and SMA" report to their offering.


  • [News Neuralstem Receives Patent for Neural Stem Cell Immortalization Technology    
    Representatives of Neuralstem have announced that the company received official "Notice of Allowance" from the U.S. Patent and Trade Office, for its technology that will immortalize stable neural stem cell lines.

  • [News Heart Patients Report Dramatic Improvement with Adult Stem Cell Therapy in Clinical Trials    
    Aaron Cathcart was told by his doctor that he barely had a year to live, because his heart was so weak that he would not be able to survive surgery. That was over two years ago.

  • [News Adult Stem Cells Treat Alzheimer's in Animals    
    Researchers at the Burnett School of Biomedical Sciences at the University of Central Florida today announced positive results in the treatment of Alzheimer's disease with adult stem cells in mice.

  • [News BrainStorm Develops New ALS Therapy    
    The adult stem cell company BrainStorm Cell Therapeutics announced today that it has entered into an agreement with Protein Production Services, a leading manufacturing contractor, in order to begin production of its therapeutic adult stem cell product for the treatment of ALS (amyotrophic lateral sclerosis, also known as Lou Gehrig's disease). The

  • [News Neuralstem Awarded Adult Stem Cell Patent    
    The company Neuralstem has announced today that it has been awarded a patent for its latest proprietary technology for an adult stem cell therapy that can be used in the treatment of neurological diseases.

  • [News Adult Stem Cells Approved for ALS Clinical Trial    
    The U.S. company Neuralstem announced today that it has won approval from the FDA to begin clinical trials for the testing of its adult stem cell therapy as a treatment for ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig's disease.

  • [News Adult Stem Cells Treat Cerebral Palsy    
    Europe's leading stem cell organization, the XCell-Center of Germany, has released results from a follow-up study in which significant improvement was seen in 67% of 45 cerebral palsy patients who were treated with their own autologous adult stem cells derived from bone marrow.

  • [News Stem cells from umbilical cord used for cerebral palsy treatment    
    Cerebral palsy is a major health problem, affecting approximately 1 in 500 newborns. It is caused by damage to the brain by lack of oxygen before birth. The scientific rationale for the use of stem cells for this condition has been discussed previously in the video Stem Cell Therapy for Cerebral Palsy.

  • [News The Washington Post report regarding our center and specialized stem cell treatment    

    Wu Stem Cells Medical Center, where Kara was treated, among the country's premier facilities for central nervous system illnesse... "We really weren't sure what to expect, but Kara got better and better every day. It was unbelievable," said Anderson, 41, a construction contractor, who funded the trip and treatment...


  • [News Mannitol Boosts Effectiveness of Potential Cord Blood Treatment for CP    
    The sugar-alcohol compound mannitol improved the therapeutic effectiveness of human umbilical cord blood cells injected into neonatal rat models of cerebral palsy, reports a new international study led by the University of South Florida. The mannitol opened the blood-brain barrier by temporarily shrinking the tight endothelial cells that make up the barrier.

  • [News Neuralstem receives approval to commence first ALS stem cell trial    
    Neuralstem, Inc. (NYSE Amex: CUR) today announced that its Phase I trial to treat Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) with its spinal cord stem cells has been approved by the Institutional Review Board (IRB) at Emory University in Atlanta, GA.

  • [News Sports Brain Trauma May Cause Disease Mimicking ALS    
    The most common form of motor neuron disease is amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease.

  • [News Neuralstem's ALS Stem Cell Treatment Featured On CNN    
    The segment featured the first footage of the procedure, in which Neuralstem's spinal cord stem cells are injected directly into the gray matter of the patient's spinal cord.

  • [News History of Cerebral Palsy in Children    
    Cerebral palsy is not a new disorder. There have probably been children with cerebral palsy as long as there have been children. But the medical profession did not begin to study cerebral palsy as a distinct medical condition until 1861.

  • [News New Treatment Helps Control Involuntary Crying and Laughing    
    Pseudobulbar affect (PBA) is a neurologic condition of involuntary, sudden and frequent episodes of laughing or crying and is quite common in patients with underlying neurologic diseases or injuries, especially those with multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS).

  • [News Individuals With Alzheimer's Disease May Lose Muscle Mass    
    Lean mass -- the weight of an individual's bones, muscles and organs without body fat -- appears to decline among patients with Alzheimer's disease, according to a report in the April issue of Archives of Neurology, one of the JAMA/Archives journals. These decreases may be associated with declines in brain volume and function.

  • [News Cellular Therapy Give Green Light To First ALS Adult Stem Cell Trial    
    FDA Gives TCA Cellular Therapy Green Light To Proceed With First ALS Adult Stem Cell Trial Using Patient's Own Stem Cells

  • [News Muscular Dystrophy Association Partnership With ALS Therapy Development Ins    
    Muscular Dystrophy Association Renews Partnership With ALS Therapy Development Institute To Develop New Treatments For Lou Gehrig's Disease

  • [News New Embryonic Stem Cell Trials Approved to Treat Rare Form of Blindness    
    In what could be a significant step forward for human embryonic stem cell science Massachusetts based Advanced Cell Technology (ACT)  has announced that the FDA have granted orphan drug status to MA09-hRPE ¨C a human embryonic stem cell (hESC) derived treatment for a rare type of blindness known as Stargardt's Macular Dystrophy.

  • [News Cerebral Palsy Statistics    
    Because cerebral palsy influences the way children develop, it is known as a developmental disability. In the United States today, more people have cerebral palsy than any other developmental disability, including Down syndrome, epilepsy, and autism.

  • [News Therapy and Treatment for Cerebral Palsy    
    Following your child's interdisciplinary assessment, the professionals providing care for your child will develop recommendations for treatment of his or her cerebral palsy. Many treatments are available to help a child function at the highest level possible. Although many treatments are available, we will touch upon a few of the most basic approaches used today to help a children with cerebral palsy achieve their optimal level of functioning.

  • [News The Cerebral Palsy and the treatment    
    The term cerebral palsy refers to any one of a number of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination but don't worsen over time.

  • [News ALS stem cell trial gets FDA go ahead    

  • [News Stem Cells Used To Reverse Paralysis In Animals    

  • [News ALS stem cell trial gets FDA go ahead    

  • [News Major ALS breakthrough-common cause of all forms of ALS discovered    
    The underlying disease process of amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease), a fatal neurodegenerative disease that paralyzes its victims, has long eluded scientists and prevented development of effective therapies. Scientists weren't even sure all its forms actually converged into a common disease process.

  • [News UPDATE 1-Neuralstem gets FDA OK to test stem cell drug in humans    
    U.S. health regulators allowed the stem-cell research company to start an early-stage human trial of its spinal cord stem cells in Lou Gehrig's disease, a fatal neuromuscular condition.

  • [News Multiple Sclerosis Research: Myelin Influences How Brain Cells Send Signals    
    The development of a new cell-culture system that mimics how specific nerve cell fibers in the brain become coated with protective myelin opens up new avenues of research about multiple sclerosis. Initial findings suggest that myelin regulates a key protein involved in sending long-distance signals.

  • [News Cerebral Palsy Diagnosis    
    How is the diagnosis of cerebral palsy made? When an infant or child has brain damage, a variety of symptoms can lead doctors and parents to suspect that something is wrong. In the first few months of life, an infant with brain damage may demonstrate some or all of the following symptoms that can indicate.

  • [News Turn 'Signals' for Neuron Growth Identified    
    A new paper scheduled for publication in the January issue of Nature Photonics describes the use of spinning microparticles to direct the growth of nerve fiber, a discovery that could allow for directed growth of neuronal networks on a chip and improve methods for treating spinal or brain injuries.

  • [News Surprisingly High Number of Adults With Severe Learning Disabilities Also Have Autism    
    New UK research on autism in adults has shown that adults with a more severe learning disability have a greater likelihood of having autism. This group, mostly living in private households, was previously 'invisible' in estimates of autism.

  • [News New Genetic Mutation for Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia    
    Unusual repeated segment responsible for more than a third of familial ALS cases worldwide. A team led by scientists from Johns Hopkins and the National Institutes of Health has discovered a new genetic mutation for amyotrophic lateral sclerosis (ALS) and a related disease called frontotemporal dementia (FTD) that appears to account for more than a third of all inherited cases of these diseases. The researchers show in a new study published online on September 21 in Neuron that this mutation, found within a gene called C9ORF72, is about twice as common as all the other mutations discovered thus far for the disease combined.

  • [News MRI Research Demonstrates ALS Attacks Multiple Parts of the Brain    
    Recently published studies by a researcher in the Faculty of Medicine & Dentistry demonstrate that ALS -- known as Lou Gehrig's disease -- damages neurons in parts of the brain responsible for cognition and behaviour.

  • [News Advanced cell technology receives fda clearance for clinical trials using embryonic stem cells to treat age related macu    

    Advanced Cell Technology, a biotechnology company based in Marlborough, Massachusetts which specializes in the development and commercialization of cell therapies for the treatment of a variety of diseases has been awarded FDA clearance to begin a clinical trial implementing human embryonic stem cells (hESCs) to treat Age-Related Macular Degeneration (AMD).


  • [News Appeals court overturns stem cell research funding ban    
    A federal appeals court on April 29 overturned a lower court's ruling banning federal funding of any research that leads to the destruction of human embryos.

  • [News Neuron-Damaging Mechanism Discovered in Mouse Model of Inherited ALS    
    New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published in the August 26th issue of the journal Neuron, describes a critical mechanistic link between a mutant protein and disease pathogenesis in an animal model of amyotrophic lateral sclerosis (ALS).

  • [News ALS improved by antioxidents    

  • [News New Hope for Diseases of Protein Folding Such as Alzheimer¡¯s, Parkinson¡¯s Diseases, ALS, Cancer and Diabetes    
    Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic lateral sclerosis (ALS), cancer, cystic fibrosis and type 2 diabetes.

  • [News Forcing Stem Cells into Circulation Results in Protection from Liver Failure in Animals    
    While previous studies showed that administration of bone marrow cells are capable of repairing livers in animal and human studies, relatively little work has been performed to augment existing means by which the body uses its own stem cells to heal the liver.

  • [News Stem Cell Model Offers Clues to Cause of Inherited ALS    

    An international team of scientists led by researchers at the University of California, San Diego School of Medicine have used induced pluripotent stem cells (iPSCs) derived from patients with amyotrophic lateral sclerosis (ALS) to reveal for the first time how reduced levels of a specific protein may play a central role in causing at least one inherited form of the disease.


  • [News Mild Obesity Appears to Improve Survival in Amyotrophic Lateral Sclerosis Patients    
    Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, may be an exception to the rule that being overweight is a health hazard. In a retrospective study of over 400 ALS patients, Massachusetts General Hospital (MGH) researchers found that those who were mildly obese survived longer than patients who were normal weight, underweight or even overweight. The study will appear in the journal Muscle & Nerve and has been published online.

  • [News Strides Made in Understanding Amyotrophic Lateral Sclerosis    
    Brandeis researchers have made a significant advance in the effort to understand amyotrophic lateral sclerosis (ALS) by successfully reversing the toxicity of the mutated protein in the familial type of the disease.

  • [News Cause Of Amyotrophic Lateral Sclerosis (ALS)    
    Two substantial studies, and articles published by The Lancet Neurology have confirmed that variations to the genes located on chromosome number nine may contribute to the development of front temporal dementia and also ALS, amyotrophic lateral sclerosis which is commonly known as Lou Gehrig's Disease. Lou Gehrig, an American baseball player with the New York Yankees, was diagnosed with ALS June 19, 1939 on his 36th birthday and the condition has bared his name ever since.

  • [News Protein-Based Biomarkers in Blood Serum Could Classify Individuals With Alzheimer's Disease    
    An initial analysis suggests that biomarkers in blood serum can be combined with clinical information to accurately classify patients with Alzheimer's disease, according to a report in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

  • [News New Discovery May Block Amyotrophic Lateral Sclerosis (ALS) Disease Process    
    In the first animal model of Amyotrophic Lateral Sclerosis (ALS), developed by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, Dr. Pandey's lab has found in fruit flies that blocking the abnormal movement of a protein made by a mutated gene called FUS also blocks the disease process.

  • [News Loss of Key Protein Boosts Neuron Loss in Amyotrophic Lateral Sclerosis    
    Amyotrophic lateral sclerosis, known as ALS or more popularly, Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death.

  • [News Decline in Cerebral Palsy Diagnoses in Premature Infants Suggests Improvements in Perinatal Care    

    Cerebral palsy is a neurodevelopmental condition that affects motor function, more often in children born prematurely. Because cerebral palsy is a result of brain injury received shortly before, during, or soon after birth, the number of infants being diagnosed with the condition is a good indicator of the quality of perinatal and neonatal care. An article soon to be published in the Journal of Pediatrics indicates that the rates of cerebral palsy have declined dramatically in the past 15 years.


  • [ALS Elizabeth Gwilliam-ALS (USA) Post on November 25, 2010    

  • [ALS Shahida Khan-ALS (England) Post on July 6, 2010    

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